Analysis of Urodynamic Indexes in Patients with Infiltrative Cervical Cancer after Nerve-sparing Radical Hysterectomy

Aim — to evaluate contractile function of urinary bladder in patients with infiltrative cervical cancer (CC) after nerve-sparing radical hysterectomy (NSRH). 90 patients with infiltrative CC were treated with NSRH (n=45), or radical hysterectomy III type (RHE III) without preservation of pelvic autonomic plexuses (n=45). While at preoperative period P1 indexes did not differ significantly between the groups, after NSRH performance, P1 values were significantly higher than P1 values in the group of patients treated with RHE III (8.29±1.1 vs 3.51±0.8 cm H2O; р<0.05). P2 indexes in patients from both groups before and after surgical treatment differed significantly and were 6.82±0.4 and 12.27±1.2 cm H2O (р<0.05) in NSRH group, and 5.44±0.6 and 10.62±1.1 cm H2O (р<0.05) in RHE III group. The P value in both patients groups before and after the surgical treatments was significantly diffe rent, and demonstrated a gradual elevation of urinary bladder pressure, especially in the patients from RHE III treated group. Urinary bladder volume at preoperative and postoperative periods in NSRH-treated group remained practically unaltered (209.78±14.2 and 216.86±14.9 ml (р>0.5) respectively), while in the patients from RHE III-treated group after surgical treatment an urinary bladder volume significantly decreased from 188.4±10.5 to 161.9±9.8 ml (р<0.05). The data of urodynamic study evidence on better preservation of urinary bladder functions in patients with infiltrative CC after NSRH than in the patients treated with RHE III.